{"id":15,"date":"2026-03-18T22:57:58","date_gmt":"2026-03-18T21:57:58","guid":{"rendered":"https:\/\/thepublichealthreview.com\/zh-tw\/2026\/03\/18\/%e4%b8%80%e7%a8%ae%e9%87%9d%e5%b0%8d%e5%b0%bc%e5%b8%95%e7%97%85%e6%af%92%e7%9a%84%e4%bf%a1%e4%bd%bf%e6%a0%b8%e7%b3%96%e6%a0%b8%e9%85%b8%e7%96%ab%e8%8b%97%e5%b1%95%e7%8f%be%e8%89%af%e5%a5%bd%e8%80%90\/"},"modified":"2026-03-18T22:59:43","modified_gmt":"2026-03-18T21:59:43","slug":"%e4%b8%80%e7%a8%ae%e9%87%9d%e5%b0%8d%e5%b0%bc%e5%b8%95%e7%97%85%e6%af%92%e7%9a%84%e4%bf%a1%e4%bd%bf%e6%a0%b8%e7%b3%96%e6%a0%b8%e9%85%b8%e7%96%ab%e8%8b%97%e5%b1%95%e7%8f%be%e8%89%af%e5%a5%bd%e8%80%90","status":"publish","type":"post","link":"https:\/\/thepublichealthreview.com\/zh-tw\/2026\/03\/18\/%e4%b8%80%e7%a8%ae%e9%87%9d%e5%b0%8d%e5%b0%bc%e5%b8%95%e7%97%85%e6%af%92%e7%9a%84%e4%bf%a1%e4%bd%bf%e6%a0%b8%e7%b3%96%e6%a0%b8%e9%85%b8%e7%96%ab%e8%8b%97%e5%b1%95%e7%8f%be%e8%89%af%e5%a5%bd%e8%80%90\/","title":{"rendered":"\u4e00\u7a2e\u91dd\u5c0d\u5c3c\u5e15\u75c5\u6bd2\u7684\u4fe1\u4f7f\u6838\u7cd6\u6838\u9178\u75ab\u82d7\u5c55\u73fe\u826f\u597d\u8010\u53d7\u6027\u53ca\u6301\u4e45\u514d\u75ab\u53cd\u61c9"},"content":{"rendered":"

\u4e00\u7a2e\u91dd\u5c0d\u5c3c\u5e15\u75c5\u6bd2\u7684\u4fe1\u4f7f\u6838\u7cd6\u6838\u9178\u75ab\u82d7\u5c55\u73fe\u826f\u597d\u8010\u53d7\u6027\u53ca\u6301\u4e45\u514d\u75ab\u53cd\u61c9<\/h1>\n

\u5c3c\u5e15\u75c5\u6bd2\u56e0\u5176\u9ad8\u6b7b\u4ea1\u7387\u4ee5\u53ca\u80fd\u5920\u5728\u52d5\u7269\u8207\u4eba\u985e\u4e4b\u9593\u50b3\u64ad\uff0c\u751a\u81f3\u4eba\u50b3\u4eba\u7684\u80fd\u529b\uff0c\u5c0d\u5168\u7403\u5065\u5eb7\u69cb\u6210\u56b4\u91cd\u5a01\u8105\u3002\u8a72\u75c5\u6bd2\u4e3b\u8981\u900f\u904e\u8759\u8760\u6216\u4e2d\u9593\u5bbf\u4e3b\u5982\u8c6c\u50b3\u64ad\uff0c\u6703\u5c0e\u81f4\u56b4\u91cd\u547c\u5438\u9053\u75be\u75c5\u548c\u8166\u708e\u3002\u8fc4\u4eca\u70ba\u6b62\uff0c\u5c1a\u7121\u7372\u6279\u7684\u75ab\u82d7\u6216\u6cbb\u7642\u65b9\u6cd5\u80fd\u5920\u5c0d\u6297\u8a72\u75c5\u6bd2\u3002<\/p>\n

\u4e00\u7d44\u7814\u7a76\u4eba\u54e1\u6e2c\u8a66\u4e86\u4e00\u7a2e\u540d\u70bamRNA-1215\u7684\u65b0\u578b\u4fe1\u4f7f\u6838\u7cd6\u6838\u9178\u75ab\u82d7\uff0c\u65e8\u5728\u9810\u9632\u8a72\u75c5\u6bd2\u3002\u56db\u5341\u540d\u5065\u5eb7\u6210\u4eba\u53c3\u8207\u4e86\u9019\u98051\u671f\u81e8\u5e8a\u8a66\u9a57\u3002\u4ed6\u5011\u5728\u56db\u9031\u9593\u9694\u5167\u63a5\u7a2e\u4e86\u5169\u5291\u75ab\u82d7\uff0c\u5291\u91cf\u5f9e10\u81f3100\u5fae\u514b\u4e0d\u7b49\u3002\u7d50\u679c\u986f\u793a\uff0c\u8a72\u75ab\u82d7\u8010\u53d7\u6027\u826f\u597d\u3002\u6700\u5e38\u898b\u7684\u526f\u4f5c\u7528\u662f\u6ce8\u5c04\u90e8\u4f4d\u8f15\u5fae\u75bc\u75db\u548c\u77ed\u66ab\u75b2\u52de\u611f\u3002\u672a\u89c0\u5bdf\u5230\u56b4\u91cd\u526f\u4f5c\u7528\uff0c\u78ba\u8a8d\u4e86\u8a72\u7522\u54c1\u7684\u5b89\u5168\u6027\u3002<\/p>\n

\u5728\u7b2c\u4e00\u5291\u63a5\u7a2e\u5f8c\u50c5\u5169\u9031\uff0c\u75ab\u82d7\u5373\u8a98\u767c\u4e86\u80fd\u5920\u4e2d\u548c\u75c5\u6bd2\u7684\u6297\u9ad4\u7522\u751f\u3002\u7b2c\u4e8c\u5291\u63a5\u7a2e\u5f8c\uff0c\u9019\u7a2e\u53cd\u61c9\u5f97\u5230\u589e\u5f37\uff0c\u4e26\u4e14\u81f3\u5c11\u6301\u7e8c\u4e00\u5e74\u3002\u8a72\u75ab\u82d7\u9084\u523a\u6fc0\u4e86\u91dd\u5c0d\u5c3c\u5e15\u75c5\u6bd2\u5176\u4ed6\u8fd1\u7de3\u682a\uff08\u5982\u5b5f\u52a0\u62c9\u570b\u7684\u682a\uff09\u4ee5\u53ca\u76f8\u95dc\u75c5\u6bd2\u4ea8\u5fb7\u62c9\u75c5\u6bd2\u7684\u514d\u75ab\u53cd\u61c9\u3002\u9019\u8868\u660e\u5b83\u53ef\u80fd\u63d0\u4f9b\u91dd\u5c0d\u591a\u7a2e\u985e\u4f3c\u75be\u75c5\u7684\u5ee3\u6cdb\u4fdd\u8b77\u3002<\/p>\n

\u6240\u6709\u6e2c\u8a66\u5291\u91cf\u7684\u514d\u75ab\u53cd\u61c9\u5747\u76f8\u7576\uff0c\u5118\u7ba1\u8f03\u9ad8\u5291\u91cf\u5728\u9577\u671f\u5167\u7dad\u6301\u4e86\u7a0d\u9ad8\u7684\u6297\u9ad4\u6c34\u5e73\u3002\u53c3\u8207\u8005\u540c\u6642\u7522\u751f\u4e86\u6297\u9ad4\u548c\u7279\u7570\u6027\u514d\u75ab\u7d30\u80de\uff0c\u9019\u5c0d\u6709\u6548\u4fdd\u8b77\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n

\u8a72\u75ab\u82d7\u63a1\u7528\u5275\u65b0\u65b9\u6cd5\uff0c\u540c\u6642\u91dd\u5c0d\u75c5\u6bd2\u7684\u5169\u7a2e\u86cb\u767d\u8cea\u800c\u975e\u4e00\u7a2e\uff0c\u5f9e\u800c\u63d0\u9ad8\u4e86\u6548\u529b\u4e26\u964d\u4f4e\u4e86\u75c5\u6bd2\u9003\u907f\u514d\u75ab\u53cd\u61c9\u7684\u98a8\u96aa\u3002\u9019\u4e9b\u9f13\u821e\u4eba\u5fc3\u7684\u7d50\u679c\u70ba\u9032\u4e00\u6b65\u8a66\u9a57\u92ea\u5e73\u4e86\u9053\u8def\uff0c\u7279\u5225\u662f\u5728\u5c3c\u5e15\u75c5\u6bd2\u7d93\u5e38\u6d41\u884c\u7684\u5730\u5340\u3002\u9019\u4e00\u9032\u5c55\u53ef\u80fd\u5728\u9810\u9632\u672a\u4f86\u75ab\u60c5\u4e2d\u767c\u63ee\u95dc\u9375\u4f5c\u7528\u3002<\/p>\n

\n

Sources<\/h2>\n

\u00c0 propos de cette \u00e9tude<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41591-026-04265-1<\/a><\/p>\n

Titre\u00a0:<\/strong> A structure-based mRNA vaccine for Nipah virus in healthy adults: a phase 1 trial<\/p>\n

Revue : <\/strong> Nature Medicine<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Aur\u00e9lie Ploquin; Rosemarie D. Mason; LaSonji A. Holman; Myra Happe; Alicia T. Widge; Laura Novik; Ana M. Ortega-Villa; Galina V. Yamshchikov; Ingelise J. Gordon; Abidemi Ola; Anita Arthur; Pamela J. M. Costner; Floreliz Mendoza; Jamie Saunders; Xioalin Wang; William R. Whalen; Joanna Utoh; Jennifer Cunningham; Lorin N. Loftus; Ashley Heimann; Katia Korzeniwsky; Shayne F. Andrew; Evan Lamb; Shruthi Shyam Sunder; Amelia Thompson; Mary McDonald; Kathryn E. Foulds; Nancy J. Sullivan; Jessica Bahorich; Emily E. Coates; Rebecca J. Loomis; Barney S. Graham; Karin Bok; Sunny Himansu; Brett Leav; Walla Dempsey; John H. Beigel; Mario Roederer; Lesia K. Dropulic; ; Maxwell Norris; Preeti Apte; Renunda Dyer; LaShawn Requilman; Justine Jones; Larisa Strom; Tatiana Beresnev; Maryam Keshtkar-Jahromi; Caitlyn Dulan; Li Ou; I-Ting Teng; Tongqing Zhou<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e00\u7a2e\u91dd\u5c0d\u5c3c\u5e15\u75c5\u6bd2\u7684\u4fe1\u4f7f\u6838\u7cd6\u6838\u9178\u75ab\u82d7\u5c55\u73fe\u826f\u597d\u8010\u53d7\u6027\u53ca\u6301\u4e45\u514d\u75ab\u53cd\u61c9 \u5c3c\u5e15\u75c5\u6bd2\u56e0\u5176\u9ad8\u6b7b\u4ea1\u7387\u4ee5\u53ca\u80fd\u5920\u5728\u52d5\u7269\u8207\u4eba\u985e\u4e4b\u9593\u50b3… \u95b1\u8b80\u5168\u6587 \u4e00\u7a2e\u91dd\u5c0d\u5c3c\u5e15\u75c5\u6bd2\u7684\u4fe1\u4f7f\u6838\u7cd6\u6838\u9178\u75ab\u82d7\u5c55\u73fe\u826f\u597d\u8010\u53d7\u6027\u53ca\u6301\u4e45\u514d\u75ab\u53cd\u61c9<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,3],"tags":[],"class_list":["post-15","post","type-post","status-publish","format-standard","hentry","category-2","category-3","entry"],"_links":{"self":[{"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/posts\/15","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":1,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/posts\/15\/revisions"}],"predecessor-version":[{"id":16,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/posts\/15\/revisions\/16"}],"wp:attachment":[{"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/media?parent=15"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/categories?post=15"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thepublichealthreview.com\/zh-tw\/wp-json\/wp\/v2\/tags?post=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}